Across Pakistan, Thailand, Canada, and Australia, methamphetamine production, trafficking, addiction, and recovery take very different forms. This investigation follows police raids, rehabilitation programs, border patrols, drug-destruction operations, clandestine laboratories, and wastewater monitoring while tracing the networks that move synthetic drugs across borders. It also examines the role of Myanmar's expanding meth trade, the challenges facing people seeking treatment, and the impact of high-potency drugs on communities. Through law enforcement, experts, treatment workers, and people affected by addiction, the episode reveals the global reach of synthetic drugs.